Is motor neuron disease stem cell treatment effective and reliable?

Motor neuron cells are responsible for transmitting the messages for voluntary movements from the brain, through the spinal cord, and finally to the nerves ending in the muscles of the targeted part of the body. In case, the motor neuron cellstend to malfunction or stop functioning altogether, it can have severely debilitating effects on various essential functions of the body.

What is a motor neuron disease?

Involuntary movements, such as breathing, along with a host of voluntary movements, such as talking, swallowing, gesturing with the hands, etc. are affected by the motor neuron disease. This disease is the result of damage caused to the nerve cells due to various sorts of neurological disorders.

Types of motor neuron disease include amyotrophic lateral sclerosis (ALS), primary lateral sclerosis (PLS), post-polio syndrome, along with progressive forms of muscular atrophy and bulbar palsy.

Although conventional treatment methods have had some form of success in helping the patient to cope with the disabling condition, motor neuron disease treatment using stem cell therapy has shown immense potential as an ideal combinational therapy.

How can you identify the symptoms of motor neuron disease?

The symptoms seen in motor neuron disease begin to worsen as the disease progresses with time. The conditionsare usually classified into three stages, namely:

·         Initial stage – The symptoms begin to display faintly.

·         Advanced stage –Several functions and parts of the body begin to malfunction. Painful weakening and frequent spasms in the muscles, along with difficulty in talking, swallowing, walking, and balancing which are also clearly noticeable.

·         End stage –Increasing body paralysis and shortness of breath.

How is motor neuron disease treated?

There are several types of conventional assistive therapies that have been marginally successful in helping the patients and their families to cope with the disabling effects of motor neuron disease.

Physiotherapy, occupational therapy, speech therapy, diet, etc. can help the patients adapt to the disabilities to acertain extent.

Stem cell treatment for motor neuron disease has shown better results. It helps to revive the malfunctioning nerve cells and repair the damaged nerve tissues. Stem cells can be easily sourced from the bone-marrow of the patients.

Stem cells have the ability to stimulate the renewal of motor neuron functioning effectively. Thus, motor neuron disease treatment using stem cells helps to improve the condition of the patients.

Innovative and Effective Stem Cell Therapy for Spinal Cord Injury

Voluntary and involuntary movements of the different muscle groups, in a human body, are controlled mainly by the nervous system. This system is a complex and immense network of nerves that connect each part of the body to the brain through the spinal cord. The spinal cord is prone to damage. An injured spinal cord leads to various types of nervous disorders - higher the severity of the spinal cord injury more the complications. Stem cell therapy for spinal cord injury can restore the severed communication between the body and brain.

What is spinal cord injury?

Spinal cord injury is the trauma which damages the spinal cord tissues and results in permanent damage to thevarious functions of the body. The spinal cord can get injured even inside the spinal canal. This canal is formed by the vertebrae which help to protect the spinal cord from damage.

Some of the spinal cord injuries cause loss of sensory, reflex and motor functions in the body. Depending on the extent of the injury, the disabling symptoms may worsen with time.

What are the signs of spinal cord injury?

The severity of a spinal cord injury depends on the damaged area. Some of the common signs and symptoms are seen in a person suffering from spinal cord injury are:

·         Sensory loss – unable to feel the temperature of a hot or cold article

·         Abnormal gait – way of walking (stride) becomes abnormal

·         Suffer periods of exaggerated reflex movement or even seizures

·         Loss of bladder and bowel control

·         Bouts of tingling or numbness in arms or legs

A paralytic condition may also be the result of spinal cord injury. Quadriplegia,(paralysis of all four limbs along with the pelvis) and‘Paraplegia’(paralysis of the pelvis, legs, and trunk) could be the outcome of a spinal cord injury.

How doesstem cell therapy treat spinal cord injury?

Spinal cord injuries tend to cause permanent disability and damage to the nerve tissues that cannot heal on their own. For spinal cord injury, stem cell treatment works by neuro-generation and neuro-protection which helps the patients to recover to a remarkable degree. Stem cell treatment helps in the formation of fresh synapses and stimulate axonal sprouting which can create new and healthy neurons. 

Is Stem Cell Therapy for Mental Retardation Actually Effective?

In simple terms, mental retardation is the condition which hampers the normal development of the child’s brain. This results in slower and arrested growth of the child’s mental and intellectual abilities.

Below average performance, slower development of mental prowess, delayed learning of communication skills result in the child being highly dependent on the family or caretakers to perform everyday tasks. The child’s social and personal behavior remains abnormal along with their health.

Stem cell therapy for mental retardation has helped to regain lost mental abilities to a significant extent.

How is mental retardation classified?

There are several levels of mental retardation which are classified according to the severity of the symptoms. These are:

• ·         Mild mental retardation – This level results in the child’s IQ being between 50 and 69. Communication skills remain almost normal even though the child takes longer to learn how to talk. They can acquire academic skills up to 5-6^th-grade levels. They are independent for self-care but are socially shy.
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• ·         Moderate mental retardation – In this level, the IQ remains between 35 and 49. Learning and understanding language is slower, and communication skill is limited. These people can be educated to do simple and repetitive jobs.  They are slow learners and can take care of themselves with supervision and minimal community support.
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• ·       Severe mental retardation – This level has an IQ between 20 and 34. There is significant motor impairment, and damage to the nervous system is also seen.
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• ·         Profound mental retardation – In this level, the IQ of the child is below 20. The child is unable to understand, respond or comply with instructions. Highly dependent on caretakers even to make small movements.

What are the symptoms of mental retardation?

Poor developmental growth also leads to:

• ·         Inability to pay attention or concentrate for long
• ·         Memory problems
• ·         Restricted communication ability
• ·         Affected fine motor and reflex movements
• ·         Underdeveloped social and behavioral skills

Can mental retardation be treated?

Mental retardation is mainly caused due to the damage to the brain tissues which control the various important functions. This can happen before birth, at childbirth or even in the early years of childhood.

Several conventional treatments in combination can help regain some of the lost abilities in the affected child, however the results of stem cell therapy for mental retardation have proven immensely effective.

Stem cell treatment for mental retardation works by stimulating the nervous system into healing its damaged tissues efficiently. 

How effective is stem cell therapy for cerebral palsy?

Cerebral Palsy (CP) is a disorder which affects body movement, posture and balance. The muscle coordination is lost, and the muscles stay tight. Damage to certain parts of the brain because of abnormal development or an injury leads to this condition.

Cerebral palsy affects thousands of children worldwide every year. A child may develop cerebral palsy in the fetal stage, after birth or even in the early years of childhood. It is basically a collective term used to describe a number of neurological conditions which affect voluntary movement and coordination in the child. Cerebral palsy treatment constitutes of rehabilitation mainly as surgery is not able to repair the damaged brain structure.

How is cerebral palsy identified?

The symptoms of cerebral palsy are similar to other types of disorder hence it takes an expertized advice to diagnose the condition as cerebral palsy. At times, the damage to the brain that develops CP is not treatable which makes the disabilities permanent.

In this condition, the children show the following symptoms:

• ·         Inability to perform voluntary movements due to lack of muscle coordination
• ·         Tightened and stiff muscles
• ·         Exaggerated reflexes
• ·         Abnormal gait/way of walking
• ·         Abnormal muscle tone floppy/stiff
• ·         Weakness in arms and legs
• ·         Inability/difficulty to speak or swallow, leading to excessive drooling
• ·         Bouts of tremors shakes and random involuntary movements
• ·         Slow development of motor skills

Apart from these symptoms, the child may also experience seizures, intellectual disability, slowed overall growth and development, hearing loss and visual impairment.

What causes cerebral palsy?

Abnormal development of certain tissues of the brain, due to an injury or other factors is known to result in the development of cerebral palsy in the child. This can also be the result of:

• Insufficient oxygen supply in the fetal stage or at birth
• Infection or injury during pregnancy
• Premature birth complications
• Neonatal encephalopathy – critical illness at birth resulting in reduced oxygen supply to brain
• Abnormal shape of the brain or its structures

How is the treatment of cerebral palsy done with stem cell therapy?

Stem cell therapy for cerebral palsy at NeuroGen Brain and Spine Institute enables the regeneration of the damaged brain cells, thereby reversing the effects of the damage to a large extent.

Stem cells are able to differentiate into several other types of cells, such as glial cells, oligodendrocytes, and others, which are essential for normal functioning of the nervous system. 

NeuroGen Brain and Spine Institute: The Best Stem Cell Therapy Centre in India

When millions of patients all over the world ailing with severe and debilitating diseases are struggling to find some relief with conventional medicine and surgical technique - stem cell therapy has come as a fresh new hope for them.

Stem cell therapy in India has been initiated by the NeuroGen Brain and Spine Institute, located in Mumbai. This Institute aims to assist patients with severe neurological disorders, such as cerebral palsy, autism, spinal cord injuries, mental retardation, muscular dystrophy, stroke along with other such disorders with stem cell therapy and offer them a better quality of life.

The institute uses a diverse regulatory approach to ensure that the stem cell treatment in India is at par with other globally recognised stem cell therapy centres all over the world. The stem cell treatment at NeuroGen has a higher success rate due to its unique combination of stem cell therapy, neuro-rehabilitation, and medicinal/surgical treatment techniques.

How is stem cell therapy at NeuroGen performed?

Stem cell treatment in India by NeuroGen involves reliable stem cell research to ensure a higher success rate for treating the patients.

At NeuroGen, stem cell treatment is performed by highly-trained and extensively experienced doctors who have had remarkable success in their previous cases.

What is stem cell treatment in India used for?

Stem cell treatment in India, by NeuroGen, involves the treatment of several severe neurological disorders, including:

1. Autism -

The intricate collection of neurological disorders, often called as ASD (autism spectrum disorder) affects the performance of the brain. This leads to a slower development of the mental abilities of the patient.

2. Cerebral palsy -

This neurological disorder affects the normal development of the brain, leading to severe disabilities in the patient.

3. Muscular dystrophy -

This is a set of around 30 hereditary diseases that result in progressive weakness and deterioration of the musculoskeletal components of the body. It causes a steady weakening of the muscles, leading to severe disability in the patient.

4. Mental retardation -

Also known as ‘intellectual disability,' this is an age-related disorder which is seen during the child’s developmental years.

5. Spinal cord injury - 

The spinal cord is the main channel for transmission of messages between the brain and the various nerves in the body. An injury to the spinal cord may result in any form of disability.

These and other such neurophysiological disorders are treated at NeuroGen Brain and Spine Institute using stem cell treatment methods.

NeuroGen Offers Effective Autism Treatment in India

Autism, also known as ASD (Autism Spectrum Disorder), is a composed group of disorders that affect the patient’s social and interactive skills. It also affects their concentration and overall behaviour severely.

A child with ASD normally displays autism symptoms before he/she turns 3. However, diagnosis can be conducted after he/she completes 3 years of age.

Although there is no known conventional treatment for this condition, still with advances stem cell research and therapy, stem cell treatment for autism is gaining popularity.

Symptoms of Autism (ASD)

It is highly advisable to arrange for an effective diagnostic test in case a child, less than three years of age, displays any of the symptoms mentioned below:
 

• Inability to communicate using non-verbal medium or through body language

 

• Inability to establish and maintain peer relationships

 

• Inability to start communication or avoid being a part of conversations

 

• Difficulty in learning spoken language

 

• Repetitive behavior

 

• Reduced human connection due to excessive attachment to inanimate objects

 

• Inability to respond when their name is called

 

• Hyperactive senses

 

• Abnormally aggressive behaviour

 

• The tendency for inflicting pain on themselves

 

• Abnormal eating habits

 

Causes of Autism (ASD)

There is no single cause of autism that medical research has been able to identify. 

 

Given below are some of the suspected causes that most medical experts believe can cause autism:

1. Structural or functional damage to nervous system

2. Genetic mutation resulting in abnormal brain development

3. Environmental factors (mercury poisoning, exposure to strong medicines, stress in mother during pregnancy, infections, etc.)
 

NeuroGen provides effective autism treatment in India with stem cell therapy

Stem cell therapy is hailed as one of the best comprehensive treatment methods for a wide range of neurological and physiological disorders, which were earlier untreatable. Stem cells are the basic ‘blank’ cells that develop into the various types of cells that are essentially required by the body.

At NeuroGen Brain and Spine Institute, stem cell treatment for autism is gaining immense popularity due to its remarkable effectiveness. Lack of sufficient oxygen to the brain during the fetal stage and the degeneration of the immune system are thought to be among the main causes of autism. Regeneration of these damaged cells has been found to be effective in reversing the effects of autism. This treatment method has shown remarkable results in improving impairments caused by this debilitating neurological condition.

Effective Treatment For Cerebral Palsy Begins With NeuroGen

Cerebral palsy is a neural disorder which affects thousands of children all around the world every year. It affects nearly 4 out of 1000 children. This disorder results in abnormal tightening of the muscles, which leads to the lack of co-ordination and inability to perform various tasks. Cerebral palsy may develop in the fetal stages, at birth or even in the early childhood.

Cerebral palsy is basically a common term used to identify a group of disorders that mainly affect the co-ordination and the ability to make voluntary movements in the affected child. Although this is not a progressive disorder which tends to worsen the condition as the child grows, this condition results in mild to severe disability due to the damage caused to the brain.

Types of cerebral palsy

There are mainly 3 types of cerebral palsy:
 

1. Spastic cerebral palsy
 

2. Dyskinetic cerebral palsy
 

3. Ataxic cerebral palsy

 

Causes of cerebral palsy

Cerebral palsy is mainly caused due to an injury to the brain or a malfunction in the brain during the development of the fetus or the child. This condition may develop in the fetal stage, at birth or within a few years after the child’s birth.

These are the causes of cerebral palsy:

1. Physical trauma/infection during pregnancy

2. Insufficient oxygen supply in fetal stage

3. Premature birth complications

4. Abnormal development and shape of brain

5. Genetic mutation of brain cells

Symptoms of cerebral palsy:

At times, the injury to the brain may not be treatable and the complications may also be permanent. 

 

Some of the common symptoms of cerebral palsy are:

1. Lack of muscle co-ordination for voluntary movements (in ataxic)

2. Tightened/stiff muscles with exaggerated reflexes (in spastic)

3. Weakness in one arm/leg with abnormal gait

4. Difficulty in controlling mouth movements

5. Motor movement problems
 

Effective treatment of cerebral palsy with stem cell therapy at NeuroGen

NeuroGen Brain and Spine Institute offers extensive treatment for cerebral palsy in India through stem cell therapy. This advanced and ultra-modern treatment method is useful for treating numerous small and major neural disorders, including various types of cerebral palsy.

Conventional treatments tend to aid the patient in adjusting to an improved lifestyle, whereas cerebral palsy treatment in India using stem cells focuses on repairing the damage to the nervous tissue and helping the child to recover from this disorder effectively.