Tuesday 26 July 2016

Stem Cells: The Best Treatment For Stroke

A stroke occurs because of a problem that disrupts the blood supply to the brain. The blood supply through the blood vessels may get disrupted, resulting in Ischemic Stroke. Sometimes there may be internal bleeding inside the brain areas, causing hemorrhagic stroke. In either of the cases, the brain cells die in large numbers. Ischemic stroke is the most common form of stroke, during which the brain suffers from both nutrient and oxygen deficiency. Stroke symptoms are evident in the form of a feeling that the world is spinning, problems associated with speaking or understanding, inability to move, loss of vision etc.

Stem Cell Stroke Treatment: The Best Option For Treating Stroke

The autologous stem cells derived and obtained from the bone marrow are transplanted into the body of the patient to induce functional recovery.  

Stem cell stroke treatment has below-given benefits.

Repair

The therapeutic cells, once transplanted, secrete the trophic factors that stimulate the endogenous mechanism, for initiating brain repair. This also makes use of the repair-inducing properties of the stem cells.

No Side Effects or Immune Rejection Response

There are no ethical issues involved with the use of bone marrow-derived regenerative cells. These cells are easily accepted by the body and do not suffer from host immune rejection. Stem cell therapy is not life threatening and generates no side effects.

Establishment of New Neural Maps and Improved Impulse Transmission

The regenerative cells enhance the brain plasticity and provide for the establishment of new neuronal maps (motor re-mapping). Cell mass transplantation increases the efferent and afferent connections between different injury sites. Hence the transmission of nerve impulses is promoted. The existing synapses (points where the 2 nerve cells join) are strengthened, silent synapses are reactivated, and the process of impulse transmission resumes to a greater extent.

Improved Angiogenesis

The unique cells also provide for greater angiogenesis or generation of new blood vessels. Hence the therapy provides for improving oxygen flow to all parts of the brain.

Lowering of Inflammation

Stem cells contribute towards lowering of inflammation. These cells help reduce leukocyte infiltration in the injured brain areas as well.

Creating Mass of Healthy Cells

The transplanted cells enhance and improve the process of endogenous Neuro-genesis. Stem cells employ different progenitor cells for enhancing Vascularization. Hence the regenerative cells directly contribute towards creating the mass of healthy neural cells in the injured brain areas.

Apart from stroke treatment, autism stem cell treatment is also available. It is carried out at leading healthcare institutes like Neurogen Brain and Spine Institute (NGBSI), autism stem cell treatment is considered to be the best treatment for the disease, as it addresses the root cause of the problem, through many different ways. Bedridden patients are able to have a much better quality of life, post stem cell therapy.

Friday 22 July 2016

Advantages of Stem Cell Therapy For Spinal Cord Injury

An injury to the spinal cord results in the loss of neurons or nervous tissues. In the aftermath of SCI, there is a loss of sensory and motor functions. The rehabilitation programs and other treatment methods of stem cell injury (SCI) used till now couldn’t help restore the loss of functionalities. Stem cells have unique renewal and differentiation capabilities, and can provide for repair of the injured spinal cord. Spinal cord injury treatment today uses the unique properties of the cells. The cells can be redirected to form the glial and the neural cells. Hence, they can replace the lost neurons.
 
There are also a number of other benefits and advantages of stem cell spinal cord injury treatment. 

These are given below.
 
● Stem cells are totipotent, which means that they can differentiate and divide to form any kind of specialized cells, including neural cells. This property of stem cells has great benefits for people suffering from spinal cord injury.
 
● They  secrete certain growth factors that provide for damage control, neural regeneration and regeneration of the neural axons, which are important for transmitting neural signals.
 
● Stem cells or the neural progenitor cells offer protection against excitotoxicity. These cells also offer protection against cellular death because of other adverse mechanisms.
 
● They  have the neuroprotective effect and create a better and healthier environment for cells.
 
● They promote the preservation of axons and hence restore the lost functions of the neural cells, in the aftermath of stem cell injury.
 
● They can lower inflammation and possess immune modulation features. These cells can stimulate the process of cellular regeneration also.
 
● They can be easily transplanted multiple times during the day, in specific and uniform dosage, all of which contain high cell counts.
 
● The MSCs or mesenchymal stem cells do not face the issue of immune-system rejection. Hence there is no necessity of HLA or Human Leukocyte Antigen matching.
 
Leading health care institutions including NeuroGen Brain and Spine Research Institute (located in Mumbai, India) offer stem cell therapy for SCI. Expert health care practitioners at the institution also provide stem cell stroke treatment and stem cell treatment for neurological disorders like Autism and Dementia, among others. Post stem cell therapy; the SCI patients show improvement in areas like trunk control, balancing, posture control, sensation, spasticity, and bladder control, and in areas of postural hypotension as well. Stem cell treatment also improves on the paralysis condition, and patients affected by quadriplegia and paraplegia show marked clinical improvements post therapy.

Advantages of Treating Autism Through Stem Cell Treatment

Autism or Autism Spectrum Disorders (ASD) are the names given to the different neurological and Neurodevelopment conditions. Autism is the most common kind of ASD affecting mankind. Neural hyperfusion and immune abnormalities affect the autistic children. Autism is characterized by obsessive behavior, impaired nonverbal and verbal communication and repetitive behavior. Children who suffer from Autism appear to be self-occupied, withdrawn and distant.
 
Autism treatment via stem cell transplantation has multiple benefits for the patients. Stem cells have self-renewal and differentiation properties, and can multiply and differentiate to form specialized cells, like the neural cells or blood vessels.
 
The major benefits of stem cell transplantation towards Autism treatment include the following:
 
● It  increases angiogenesis (formation of new blood vessels).
 
● As the MSCs or the Mesenchymal Stem Cells do not suffer from rejection; there is no need to match the HAL or Human Leukocyte Antigen.
 
● Immune deregulation, as found in Autism patients, causes systemic and intestinal abnormalities and also adversely influences neurological functions. Administration and transplantation of stem cells shut-off the abnormal autoimmune responses.
 
● Stem cells produce a range of growth and trophic factors. These factors provide for repair and regeneration of the damaged cells, including neural cells. The secretion of these substances from the transplanted stem cells also creates a favorable environment for cellular growth and multiplication.
 
● Administration of MSCs improves sensory aspects, reduces unusual and abnormal sensitivity to the different sensory stimuli, and also improves on abnormalities like abnormal vision, touching and insensitiveness towards pain.

● Stem cell possesses healing properties like immune modulation, can lower inflammation and can also stimulate regeneration.
 
● The stem cells can be easily administered a number of times during a day for Autism treatment, in uniform dosage forms, all having greater cell counts.
 
One of the leading institutions, NeuroGen Brain and Spine Institute (NGBSI) offers stem cell therapy for Autism and other neural and muscular disorders. When combined with a rehabilitation program that offers patients therapies like Speech, Yoga, Dance and Music, Occupational and other therapies, stem cell treatment can improve the life of Autism patients in many ways. Apart from the treatments for Cerebral Palsy, Dementia, and  Spinal Cord Injury,  one can also avail motor neuron disease stem cell treatment at this leading health care institution.