Thursday 10 October 2019

Muscular Dystrophy Treatment at Neurogen Hospital

Muscular dystrophy is a myriad of progressive diseases that result in weakness and loss of muscle mass. It is caused due to genes
mutations which interfere with the production of ‘dystrophin’, a protein needed to build healthy muscle.
There is no complete cure for muscular dystrophy, but with cell therapy for muscular dystrophy, there is a possibility of managing
the symptoms and slowing down the muscle deterioration. 
The mutation of the genes and loss of dystrophin leads to a sequence of dysfunctional developments causing severe and progressive
muscle-wasting skeletal muscles and heart muscles. These skeletal muscles are responsible for voluntary body movements. As they
weaken people with muscular dystrophy lose their ability to walk or do manual work. They experience muscle spasms (twitches or cramps)
that are painful and make fine muscle control more difficult. If the patients do not receive treatment, they may develop slack muscle
and an enlarged heart with chances of heart failure.
Signs and Symptoms 
  • Loss of balance resulting in frequent falls
  • Difficulty when rising from a lying or sitting position
  • Unable to run or jump
  • Walk with a waddling gait
  • Walk on the toes
  • Enlarged calf muscles
  • Frequent muscle pain 
  • Muscle stiffness
  • Learning disabilities


Muscular dystrophy treatment with stem cells is done at NeuroGen Brain and Spine Institute by renowned surgeons guided by Dr. Alok Sharma.
With years of experience and expertise, Dr. Alok Sharma is amongst the top-ranked neurosurgeon in India. Holding a supreme position in NGBSI,
his area of specialization is neurosurgery with stem cells. 
The treatment for muscular dystrophy involves the use of bone marrow-derived mesenchymal stem cells. The regenerative and anti-inflammatory properties of stem cells are considered as a good treatment option for muscular dystrophy.  The doctor at the hospital confirms that cell therapy for muscular dystrophy has the potential to create muscle protein and also helps to halt the progressive muscle deterioration. For treating the patients, the doctors remove the bone marrow from the hip bone of the patient. The marrow tissue is subjected to a stem cell separation procedure at their fully equipped GPL and GMP laboratory. The separated useful stem cells are administered into the muscles points using a thin needle.
The healthy stem cells, transplanted into the muscles, generate healthy cells into the diseased muscle. They substantially improve the ability of the muscles by replenishing the weak cell pool, and also provide a continuous generation of healthy stem cells. Thus, muscular dystrophy treatment with mesenchymal stem cells repairs the muscle without fear of cell rejection and tumor formation.
Successful cell therapy for muscular dystrophy should be done before the muscle cells get completely depleted.