Autologous Cell Transplant for People with Stroke

A stroke is a ‘brain attack’ which occurs if the blood flow to an area of the brain is cut off. The brain cells begin to die as they are deprived
of fresh oxygen supply. As they die, their ability to control the person’s memory and muscle movement get completely lost. The level of
stroke severity depends on the area and the extent of brain damage. Thus, stroke is a neurological disorder caused by the loss of neurons
or glial cells of the brain. Cell treatment for stroke is an innovative therapy to treat people with their own stem cells. 

Types of Stroke

Haemorrhagic stroke

A haemorrhagic stroke occur when weak blood vessels burst to spill blood. This results in the swelling and damage of the tissue and cells. 

Ischemic Stroke

If the blood vessels become narrow or get by a blood clot (ischemic), it causes reduced fresh blood supply to the brain.  

A transient ischemic attack (TIA) 

A transient ischemic attack is just like a stroke. It has similar symptoms but lasts only for a short period. This ‘mini-stroke’ causes no permanent
damage but acts as a warning for a serious stroke.

Cell treatment for stroke helps to generate new neurons and glia in patients suffering from a stroke. Stem cell-based therapy at
NeuroGen Brain and Spine Institute is accomplished using mesenchymal stem cells to treat a variety of damaged brain tissues.
Easily accessible in the marrow tissue, these cells are exceedingly suitable for autologous cell-based therapies. As they are derived
from the patient’s own body (autologous), they do not face issues like rejection while merging with other stem cells.  

Thus, for stroke cell treatment has helped in preventing the death of brain cells by promoting regeneration and repair of
defective tissues, nerve, and cells.  

Transplantation of mesenchymal stem cells involves just three simple steps:

• Collecting the marrow from the hip bone of the patient
• Purifying and filtering the cells through ‘density gradient centrifugation’ procedure
• Infusion of the filtered stem cells after being diluted in CSF 

At the hospital, for people with stroke cell treatment is an intrathecal administration of mesenchymal stem cells in the spinal area.

When infused in the body, these cells migrate through the vertebral canal to reach the site of injured brain tissue.
They begin their healing process to stop further tissue deterioration and to generate new cells to replace the dead ones. As the tissue
gets healed the brain regains its lost plasticity.

Thus, cell treatment for stroke is a promising way of promoting the interest of people towards regenerative medicine