Tuesday 7 January 2020

Mesenchymal Stem Cells - An Anti-Inflammatory Treatment for Muscular Dystrophy

Duchenne muscular dystrophy is a progressive and lethal muscular-degenerative condition which is caused by the mutation of the dystrophin gene. Cell therapy for muscular dystrophy is the only intervention that can mediate improvement in patients. 
Without the essential dystrophin, muscle fibres are highly vulnerable to damage and easy succumbing, affecting the normal daily activities in patients.  This muscle damage is easily repaired with autologous mesenchymal stem cells that have the potential to address this progressive degeneration in muscular dystrophy muscles. Thus, cell transplantation is the best muscular dystrophy treatment approach to reverse the damage of degenerated muscle-cells in patients with muscular dystrophy.
Mesenchymal stem cells are multipotent cells that can be easily sourced from the marrow tissue. They have the capacity to repair bone, brain cell tissue, blood vessel, and muscular-skeletal tissue. These cells have shown great promise for patients with muscular dystrophy in NeuroGen BSI hospital where the neurosurgeons confirm the safety of muscular dystrophy treatment with intrathecal injection of mesenchymal stem cells in the spinal area.
The trained surgeons and staff at the NeuroGen BSI  have stated amazing symptomatic improvement in 90% of their muscular dystrophy patients.  They have a vast experience of treating individuals with degenerative muscle diseases, spinal cord injury and those disturbed with neurological conditions. Thus, mesenchymal cell therapy for muscular dystrophy is an emerging regenerative medicine that focuses on treatment providing improved limb and muscle coordination.
People who inquire about the advantage of cell treatment with mesenchymal stem cells (in contrast to other cell-based therapies) must know the underlying benefits:  
  • The ability to fuse and genetically balance dystrophic deficiency in muscle
  • They possess anti-inflammatory factors
  • They produce trophic factors that enhance the activity of cell repair

With the above-mentioned properties, the neurosurgeons prefer mesenchymal stem cell therapy for muscular dystrophy as they have the advantages of correcting the dystrophin deficiency in muscle cells and also in regaining the muscle tone, flexibility, strength and a balanced gait.

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